Flucloxacillin 250 Mg Austell 250 mg Capsules

Flucloxacillin 250 Mg Austell 250 mg Capsules

S4
PDF Leaflet Revision Date: 21 November 2024


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of infections caused by susceptible Gram-positive organisms.

Dosage (summary)

Adults: 250 mg four times daily; may double in severe infections.

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Not established; avoid in pregnancy and breastfeeding.

Key Drug Interactions

  • Probenecid
  • Sulfinpyrazone
  • Methotrexate
  • Warfarin
  • Paracetamol

Contraindications

  • Hypersensitivity to flucloxacillin
  • Previous flucloxacillin associated jaundice

Common side effects

  • Neutropenia
  • Thrombocytopenia
  • Rash
  • Nausea
  • Diarrhea

Counselling Points

  • Take 1 hour before meals
  • Monitor for hypersensitivity reactions
  • Avoid in severe renal impairment

Serious warnings

  • Risk of anaphylaxis
  • Hepatic reactions
  • AGEP
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