Solonex- Co 300mg Tablet
PDF Leaflet Revision Date: 12 August 2012
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of active tuberculosis in high-risk adults and children.
Dosage (summary)
Adults: 15 mg/kg (max 900 mg) once weekly for 12 weeks. Children: 25 mg/kg (max 900 mg) once weekly for 12 weeks.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; contraindicated in breastfeeding.
Key Drug Interactions
- Protease inhibitors
- NNRTIs
- Hormonal contraceptives
Contraindications
- Hypersensitivity to isoniazid or rifapentine
- Acute or chronic liver disease
- Severe renal failure
- Alcoholism
- Seizure disorders
Common side effects
- Nausea
- Headache
- Hepatitis
- Skin reactions
Counselling Points
- Take with food
- Adhere to treatment regimen
- Monitor for hypersensitivity reactions
Serious warnings
- Hepatotoxicity
- Severe cutaneous adverse reactions
- Clostridium difficile-associated diarrhoea
Important Disclaimer
The Solonex- Co 300mg Tablet professional information leaflet below is the property of Macleods Pharmaceuticals Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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