Aluvia 100/25 FC Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in combination with other antiretroviral agents.
Dosage (summary)
The recommended dose for adults is 400 mg Lopinavir/100 mg Ritonavir taken twice daily, with or without food.
Onset of Action / Duration
Therapeutic effects may be observed within 1-2 weeks of starting treatment, but optimal viral suppression may take longer.
Special Populations
- Hepatic impairment
- Renal impairment
- Pediatric patients
- Elderly patients
Pregnancy & Breastfeeding
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lopinavir/Ritonavir is excreted in breast milk; breastfeeding is not recommended.
Key Drug Interactions
- Caution with drugs that are strong CYP3A4 inducers or inhibitors.
- Avoid use with certain antiarrhythmics, anticonvulsants, and other antiretrovirals.
Contraindications
- Hypersensitivity to Lopinavir, Ritonavir, or any component of the formulation.
- Severe hepatic impairment.
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Fatigue
- Hyperlipidemia
Counselling Points
- Take the medication exactly as prescribed.
- Do not skip doses; adherence is crucial for treatment efficacy.
- Inform healthcare provider of all medications being taken.
- Monitor for signs of liver dysfunction or allergic reactions.
Serious warnings
- Risk of pancreatitis.
- Potential for drug interactions leading to increased toxicity.
- Monitor lipid levels regularly.
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