Uromitexan 400 Mg Injection 400 mg Injection

Uromitexan 400 Mg Injection 400 mg Injection

S4
PDF Leaflet Revision Date: 28 October 2022


Clinical Summary

Quick overview from the medicine insert

Indication

Reduces urinary toxicity from oxazaphosphorines.

Dosage (summary)

IV injection of 20% of oxazaphosphorine dose at 0, 4, and 8 hours.

Special Populations

  • Elderly patients
  • Paediatric patients (<16 years)

Pregnancy & Breastfeeding

Not established; avoid in pregnancy and lactation.

Key Drug Interactions

  • Incompatible with cisplatin, carboplatin, nitrogen mustard
  • Inactivates epirubicin

Contraindications

  • Hypersensitivity to UROMITEXAN or thiol compounds

Common side effects

  • Headache
  • Infusion site reactions
  • Abdominal pain
  • Light-headedness
  • Nausea

Counselling Points

  • Monitor for hypersensitivity reactions
  • Maintain adequate hydration
  • Inspect for particulate matter before use

Serious warnings

  • Potential for severe hypersensitivity reactions
  • Does not prevent all adverse effects of oxazaphosphorines
Important Disclaimer

The Uromitexan 400 Mg Injection 400 mg Injection professional information leaflet below is the property of Baxter Healthcare South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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