Avoxa 400 mg FC tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of bacterial infections including respiratory tract infections, skin and soft tissue infections, and intra-abdominal infections.
Dosage (summary)
The usual adult dosage is 400 mg once daily, administered orally, with or without food.
Onset of Action / Duration
Onset of action typically occurs within 1 to 2 hours after administration.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Moxifloxacin should be avoided during pregnancy and lactation unless the potential benefit justifies the potential risk to the fetus or infant.
Key Drug Interactions
- Antacids containing magnesium or aluminum may reduce the absorption of Moxifloxacin.
- Concurrent use with anticoagulants may increase the risk of bleeding.
- Caution with other QT-prolonging drugs.
Contraindications
- Hypersensitivity to Moxifloxacin or any other quinolone antibiotics.
- History of tendon disorders related to fluoroquinolone use.
- Pregnancy and lactation.
Common side effects
- Nausea
- Diarrhea
- Dizziness
- Headache
- QT interval prolongation
Counselling Points
- Take the medication at the same time each day.
- Avoid taking with dairy products or calcium-fortified juices.
- Report any signs of tendon pain or swelling immediately.
- Stay hydrated and report any severe diarrhea.
Serious warnings
- May cause serious allergic reactions.
- Risk of Clostridium difficile-associated diarrhea.
- Use with caution in patients with a history of seizures.
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