Granupas 5,52 g Powder for oral solution.
PDF Leaflet Revision Date: 28 May 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of Multidrug Resistant TB (MDR-TB).
Dosage (summary)
Adults: 8-12 g daily in 2-3 doses; <50 kg: 4-8 g daily.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Isoniazid
- Uricosuric medicines
- Ethionamide
- Anticoagulants
- Rifampicin
Contraindications
- Hypersensitivity
- Moderate/severe renal impairment
- Severe hepatic impairment
- Severe heart failure
- Gastroduodenal ulcer
- Hypothyroidism
- Phenylketonuria
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Anorexia
Counselling Points
- Take after meals to reduce gastric irritation.
- Monitor for signs of liver toxicity.
- Avoid in pregnancy and breastfeeding.
Serious warnings
- Risk of hepatotoxicity
- Caution in renal impairment
- Caution in heart failure
Important Disclaimer
The Granupas 5,52 g Powder for oral solution. professional information leaflet below is the property of Ipharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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