Hypopress 10 10 mg/ml Solution for injection or infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
For increasing blood pressure in adults with clinically significant hypotension.
Dosage (summary)
IV bolus: 10 mg diluted to 200 ml; Continuous infusion: 10 mg diluted in 500 ml.
Onset of Action / Duration
Onset: Immediate, Duration: 15-20 mins
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
- Paediatric population
Pregnancy & Breastfeeding
Safety during pregnancy and lactation not established; avoid use in breastfeeding.
Key Drug Interactions
- MAO inhibitors
- Indirect sympathomimetics
- Alpha sympathomimetics
- Halogenated volatile anaesthetics
Contraindications
- Hypersensitivity to phenylephrine
- Severe uncontrolled hypertension
- Hyperthyroidism
- Heart block
- Uncontrolled cardiac failure
- Bradycardia
Common side effects
- Headache
- Bradycardia
- Hypertension
- Nausea
- Vomiting
Counselling Points
- Administer under supervision of trained professionals
- Monitor for signs of hypotension
- Avoid extravasation during injection
Serious warnings
- Risk of severe hypotension upon sudden cessation
- Caution in patients with cardiovascular disease
- Monitor blood pressure during treatment
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