Axorn Co FC Tablet

Indication

Management of hypertension and heart failure.

Dosage (summary)

The usual starting dose is 80 mg/12.5 mg once daily, which may be adjusted based on blood pressure response. Maximum dose can be 320 mg/25 mg once daily.

Onset of Action / Duration

Antihypertensive effects can be observed within 2 weeks of starting treatment, with maximum effect typically seen after 4-6 weeks.

Special Populations

• Elderly patients may require dose adjustment.
• Patients with renal impairment should be monitored closely.
• Patients with hepatic impairment should use with caution.

Pregnancy & Breastfeeding

Use is contraindicated during pregnancy and lactation due to potential harm to the fetus and nursing infant.

Key Drug Interactions

• Potassium-sparing diuretics may increase the risk of hyperkalemia.
• Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effect.
• Other antihypertensive agents may have additive effects.

Contraindications

• Hypersensitivity to valsartan, hydrochlorothiazide, or any component of the formulation.
• Severe renal impairment.
• Anuria.
• Pregnancy and lactation.

Common side effects

• Dizziness.
• Fatigue.
• Hypotension.
• Electrolyte imbalances (e.g., hypokalemia, hyperkalemia).
• Renal impairment.

Counselling Points

• Take the medication at the same time each day.
• Monitor blood pressure regularly.
• Report any signs of allergic reactions, such as rash or swelling.
• Maintain adequate hydration and electrolyte balance.