Vondip Iv 200 mg. Powder for solution for infusion.
PDF Leaflet Revision Date: 10 March 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment and prophylaxis of invasive fungal infections.
Dosage (summary)
Loading: 6 mg/kg every 12 hours for 24 hours; Maintenance: 3-4 mg/kg every 12 hours.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; effective contraception required.
Key Drug Interactions
- CYP3A4 substrates
- Phenytoin
- Rifampicin
- Efavirenz
Contraindications
- Hypersensitivity to voriconazole
- Severe hepatic impairment
- Concurrent use with certain CYP3A4 substrates
Common side effects
- Visual disturbances
- Nausea
- Rash
- Elevated liver enzymes
Counselling Points
- Monitor for visual changes
- Avoid sun exposure
- Report any rash or liver symptoms
Serious warnings
- Hepatotoxicity
- QT prolongation
- Infusion-related reactions
Important Disclaimer
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