Actraphane Hm injection
Clinical Summary
Quick overview from the medicine insert
Indication
Management of diabetes mellitus in adults and children.
Dosage (summary)
Dosage is individualized based on the patient's needs, typically administered subcutaneously. The usual starting dose is 0.5 to 1.0 units/kg/day, divided into two doses.
Onset of Action / Duration
Onset: 30 minutes; Peak: 2 to 8 hours; Duration: 24 hours.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Insulin is generally considered safe during pregnancy and lactation. Close monitoring of blood glucose levels is essential.
Key Drug Interactions
- Beta-blockers may mask hypoglycemic symptoms.
- Thiazide diuretics may increase blood glucose levels.
- Alcohol can potentiate the hypoglycemic effect.
Contraindications
- Hypersensitivity to insulin or any of the excipients.
- Severe hypoglycemia.
Common side effects
- Hypoglycemia
- Weight gain
- Injection site reactions
- Allergic reactions
Counselling Points
- Instruct patients on proper injection techniques.
- Advise on recognizing signs and symptoms of hypoglycemia.
- Emphasize the importance of regular blood glucose monitoring.
Serious warnings
- Risk of hypoglycemia, especially if meals are missed or delayed.
- Patients should be cautious when driving or operating machinery until they know how insulin affects them.
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