Adco Labetalol injection
Clinical Summary
Quick overview from the medicine insert
Indication
Management of hypertension, including hypertensive emergencies.
Dosage (summary)
Initial dose of 5 to 20 mg IV, may be repeated every 10 minutes as needed, with a maximum dose of 300 mg in 24 hours.
Onset of Action / Duration
Onset of action is typically within 5 minutes; duration of effect is approximately 2 to 4 hours.
Special Populations
- Elderly patients
- Patients with hepatic impairment
- Patients with renal impairment
Pregnancy & Breastfeeding
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Labetalol is excreted in breast milk; caution is advised when administered to nursing mothers.
Key Drug Interactions
- Other antihypertensive agents may have additive effects.
- Caution with concurrent use of beta-blockers.
- May interact with drugs that affect hepatic metabolism.
Contraindications
- Asthma or severe bronchospastic disease
- Severe bradycardia
- Heart block greater than first degree
- Cardiogenic shock
- Decompensated heart failure
Common side effects
- Dizziness
- Fatigue
- Nausea
- Hypotension
- Bradycardia
Counselling Points
- Monitor blood pressure regularly during treatment.
- Inform healthcare provider of any history of asthma or heart conditions.
- Avoid abrupt discontinuation to prevent rebound hypertension.
Serious warnings
- Caution in patients with diabetes as it may mask hypoglycemia.
- Monitor for signs of liver dysfunction.
- Use with caution in patients with a history of allergic reactions.
Important Disclaimer
The Adco Labetalol injection professional information leaflet below is the property of Adcock Ingram Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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