Akineton Tablets & Injection
PDF Leaflet Revision Date: 25 June 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Management of Parkinsonism and drug-induced extrapyramidal symptoms.
Dosage (summary)
Tablets: 1-4 mg 3-4 times daily; Ampoules: 10-20 mg IM/IV for severe cases.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established for safety in pregnancy and lactation.
Key Drug Interactions
- Anticholinergic drugs
- Antidepressants
- Neuroleptics
- Levodopa
Contraindications
- Hypersensitivity to biperiden
- Narrow angle glaucoma
- Ileus
- Megacolon
- Cerebral impairment crisis
- Myasthenia gravis
Common side effects
- Dizziness
- Dry mouth
- Fatigue
- Memory impairment
- Urinary retention
Counselling Points
- Avoid alcohol
- May impair reaction times
- Monitor for withdrawal symptoms
Serious warnings
- Risk of severe bradycardia
- Potential for dependency
- Caution in CNS impairment
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