Suprefact 3-Month Depot 3.3mg. 9.9mg Implant

Suprefact 3-Month Depot 3.3mg. 9.9mg Implant

S4
PDF Leaflet Revision Date: 06 June 2018


Clinical Summary

Quick overview from the medicine insert

Indication

Advanced prostatic cancer requiring testosterone suppression.

Dosage (summary)

One implant (9.45 mg buserelin) subcutaneously every 3 months.

Onset of Action / Duration

Onset: 2-4 weeks, Duration: 3 months

Special Populations

  • Patients with hypertension
  • Diabetic patients
  • History of depression

Pregnancy & Breastfeeding

Not recommended; safety not established.

Key Drug Interactions

  • Antidiabetic medicines
  • QT prolonging drugs

Contraindications

  • Hypersensitivity to buserelin acetate
  • Post-surgical testosterone suppression

Common side effects

  • Loss of libido
  • Hot flushes
  • Dizziness
  • Injection site pain

Counselling Points

  • Monitor blood pressure and glucose levels
  • Report any signs of depression
  • Avoid driving if experiencing dizziness

Serious warnings

  • Risk of osteoporosis
  • Monitor for QT prolongation
  • Adjunctive anti-androgen therapy recommended
Important Disclaimer

The Suprefact 3-Month Depot 3.3mg. 9.9mg Implant professional information leaflet below is the property of Pharmaco Distribution and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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