Alond Capsules
Clinical Summary
Quick overview from the medicine insert
Indication
Management of neuropathic pain, generalized anxiety disorder, and as an adjunctive therapy for partial seizures.
Dosage (summary)
Initial dose is typically 75 mg twice daily, which may be increased to 150 mg twice daily based on clinical response.
Onset of Action / Duration
Analgesic effects may be observed within 1 week, while maximum effect may take several weeks.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Pregabalin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk; caution is advised when administered to nursing mothers.
Key Drug Interactions
- CNS depressants (e.g., opioids, benzodiazepines) may enhance sedative effects.
- Antacids may reduce the absorption of Pregabalin.
Contraindications
- Hypersensitivity to Pregabalin or any of its components
- Severe renal impairment (CrCl < 30 mL/min) without dose adjustment
Common side effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Weight gain
- Blurred vision
Counselling Points
- Advise patients to avoid abrupt discontinuation to prevent withdrawal symptoms.
- Inform patients about the potential for dizziness and sedation; caution when driving or operating machinery.
- Encourage patients to report any signs of mood changes or suicidal thoughts.
Serious warnings
- Risk of misuse, abuse, and dependence.
- May cause serious allergic reactions.
- Monitor for signs of angioedema.
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