Aluvia 100/25 FC Tablets

Aluvia 100/25 FC Tablets

S4

API: Lopinavir / Ritonavir | Company: AbbVie

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of HIV-1 infection in combination with other antiretroviral agents.

Dosage (summary)

The recommended dose for adults is 400 mg Lopinavir/100 mg Ritonavir taken twice daily, with or without food.

Onset of Action / Duration

Therapeutic effects may be observed within 1-2 weeks of starting treatment, but optimal viral suppression may take longer.

Special Populations

  • Hepatic impairment
  • Renal impairment
  • Pediatric patients
  • Elderly patients

Pregnancy & Breastfeeding

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lopinavir/Ritonavir is excreted in breast milk; breastfeeding is not recommended.

Key Drug Interactions

  • Caution with drugs that are strong CYP3A4 inducers or inhibitors.
  • Avoid use with certain antiarrhythmics, anticonvulsants, and other antiretrovirals.

Contraindications

  • Hypersensitivity to Lopinavir, Ritonavir, or any component of the formulation.
  • Severe hepatic impairment.

Common side effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Fatigue
  • Hyperlipidemia

Counselling Points

  • Take the medication exactly as prescribed.
  • Do not skip doses; adherence is crucial for treatment efficacy.
  • Inform healthcare provider of all medications being taken.
  • Monitor for signs of liver dysfunction or allergic reactions.

Serious warnings

  • Risk of pancreatitis.
  • Potential for drug interactions leading to increased toxicity.
  • Monitor lipid levels regularly.
Important Disclaimer

The Aluvia 100/25 FC Tablets professional information leaflet below is the property of AbbVie and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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