Arixtra 2.5 mg/0.5 ml Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention and treatment of venous thromboembolic events and acute coronary syndromes.
Dosage (summary)
2.5 mg once daily by subcutaneous injection; initial dose 6 hours post-surgery.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Body weight < 50 kg
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- NSAIDs
- Platelet inhibitors
- Fibrinolytics
Contraindications
- Hypersensitivity to fondaparinux
- Active major bleeding
- Severe renal impairment
- Infective endocarditis
- Body weight < 50 kg
Common side effects
- Bleeding
- Thrombocytopenia
- Nausea
- Headache
Counselling Points
- Administer subcutaneously, not intramuscularly.
- Monitor for signs of bleeding.
- Strict adherence to dosing schedule is crucial.
Serious warnings
- Risk of spinal/epidural hematomas
- Increased risk of bleeding in renal impairment
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