Aspen Pantoprazole Injection

Indication

Treatment of gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome.

Dosage (summary)

40 mg administered intravenously once daily.

Onset of Action / Duration

Onset of action typically occurs within 1 to 2 hours, with a duration of effect lasting up to 24 hours.

Special Populations

• Elderly patients may require dose adjustment.
• Patients with hepatic impairment should use with caution.
• Patients with renal impairment do not require dose adjustment.

Pregnancy & Breastfeeding

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Pantoprazole is excreted in breast milk; caution should be exercised when administered to nursing mothers.

Key Drug Interactions

• May reduce the absorption of drugs requiring an acidic pH for absorption (e.g., ketoconazole, atazanavir).
• Caution with concomitant use of warfarin, as it may increase the risk of bleeding.

Contraindications

• Hypersensitivity to pantoprazole or any component of the formulation.
• Severe hepatic impairment.

Common side effects

• Headache
• Diarrhea
• Nausea
• Abdominal pain
• Dizziness

Counselling Points

• Inform patients to report any signs of allergic reactions, such as rash or difficulty breathing.
• Advise patients to take the medication as prescribed and not to exceed the recommended dose.
• Encourage patients to maintain a healthy diet and lifestyle to support treatment.