Bertred Injection
PDF Leaflet Revision Date: 24 March 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of multiple myeloma and mantle cell lymphoma.
Dosage (summary)
Starting dose: 1.3 mg/mu00b2 twice weekly for 2 weeks, followed by a 10-day rest.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid use during pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Oral hypoglycaemics
Contraindications
- Hypersensitivity to bortezomib
- Acute pulmonary disease
Common side effects
- Nausea
- Diarrhoea
- Constipation
- Fatigue
- Thrombocytopenia
Counselling Points
- Monitor for signs of neuropathy
- Avoid intrathecal administration
- Use effective contraception during treatment
Serious warnings
- Herpes zoster reactivation
- Progressive multifocal leukoencephalopathy
- Posterior reversible encephalopathy syndrome
Important Disclaimer
The Bertred Injection professional information leaflet below is the property of Dr Reddy’S Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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