Bio Metronidazole Injection
PDF Leaflet Revision Date: 20 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment and prevention of anaerobic infections.
Dosage (summary)
100 mL (500 mg) IV every 8 hours for treatment; same dose for prevention before and after surgery.
Special Populations
- Hepatic impairment
- Renal impairment
- Paediatric population
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Alcohol
- Warfarin
- Lithium
- Ciclosporin
- Busulfan
Contraindications
- Hypersensitivity to metronidazole
- End stage liver damage
- Blood dyscrasias
- Active CNS diseases
Common side effects
- Nausea
- Dizziness
- Headache
- Peripheral neuropathy
- Leukopenia
Counselling Points
- Avoid alcohol during and 1-3 days after treatment
- Monitor for signs of liver injury
- Report any CNS symptoms immediately
Serious warnings
- Hepatic impairment caution
- Potential for severe hepatotoxicity
- Risk of CNS toxicity with prolonged use
Important Disclaimer
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