Bemetrazole Tablets

Indication

Treatment of infections caused by anaerobic bacteria and certain protozoa, including bacterial vaginosis, trichomoniasis, and amebiasis.

Dosage (summary)

200 mg to 400 mg, taken orally, usually 2 to 3 times daily for 5 to 10 days depending on the infection being treated.

Onset of Action / Duration

Onset of action typically occurs within 1 to 2 hours after administration.

Special Populations

• Patients with liver impairment
• Elderly patients
• Patients with renal impairment

Pregnancy & Breastfeeding

Metronidazole is classified as Category B2 for pregnancy. It should be used during pregnancy only if clearly needed. It is excreted in breast milk; caution is advised when administering to nursing mothers.

Key Drug Interactions

• Alcohol: Concurrent use may cause a disulfiram-like reaction.
• Warfarin: May enhance the anticoagulant effect.
• Lithium: May increase lithium levels.

Contraindications

• Hypersensitivity to metronidazole or any component of the formulation.
• History of blood dyscrasias.
• First trimester of pregnancy (unless absolutely necessary).

Common side effects

• Nausea
• Headache
• Dizziness
• Diarrhea
• Metallic taste
• Abdominal cramps

Counselling Points

• Avoid alcohol during treatment and for at least 48 hours after completing therapy.
• Take the medication with food to minimize gastrointestinal upset.
• Complete the full course of therapy even if symptoms improve.