Bio Metronidazole Iv 100 ml Solution for infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment and prevention of anaerobic infections.
Dosage (summary)
100 mL (500 mg) IV every 8 hours for treatment; same dose for prevention before and after surgery.
Special Populations
- Hepatic impairment
- Renal impairment
- Paediatric population
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Alcohol
- Warfarin
- Lithium
- Ciclosporin
- Busulfan
Contraindications
- Hypersensitivity to metronidazole
- End stage liver damage
- Blood dyscrasias
- Active CNS diseases
Common side effects
- Nausea
- Dizziness
- Headache
- Peripheral neuropathy
- Leukopenia
Counselling Points
- Avoid alcohol during and 1-3 days after treatment
- Monitor for signs of liver injury
- Report any CNS symptoms immediately
Serious warnings
- Hepatic impairment caution
- Potential for severe hepatotoxicity
- Risk of CNS toxicity with prolonged use
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