Borturas 3,5mg injection
PDF Leaflet Revision Date: 20 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of multiple myeloma and relapsed mantle cell lymphoma.
Dosage (summary)
1.3 mg/mu00b2 twice weekly for 2 weeks, then 10-day rest; adjust for toxicity.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid breastfeeding during treatment.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Oral hypoglycemics
Contraindications
- Hypersensitivity to bortezomib
- Acute pulmonary disease
Common side effects
- Nausea
- Diarrhea
- Fatigue
- Thrombocytopenia
- Peripheral neuropathy
Counselling Points
- Monitor for signs of neuropathy
- Avoid driving if experiencing dizziness
- Use contraception during treatment
Serious warnings
- Risk of intrathecal administration
- Gastrointestinal toxicity
- Cardiac failure
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