Caduet 5 mg/10 mg, 5 mg/20 mg, 10 mg/10 mg, 10 mg/20 mg, 10 mg/40 mg, 10 mg/80 mg Film-coated tablet
Clinical Summary
Quick overview from the medicine insert
Indication
For patients at increased cardiovascular risk due to hypertension and dyslipidaemia.
Dosage (summary)
5 mg/10 mg to 10 mg/80 mg once daily, individualized based on effectiveness and tolerance.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; use effective contraception.
Key Drug Interactions
- CYP3A4 inhibitors
- Ciclosporin
- Fibric acid derivatives
Contraindications
- Hypersensitivity to components
- Active liver disease
- Pregnancy
- Severe hypotension
Common side effects
- Dizziness
- Headaches
- Nausea
- Myalgia
- Fatigue
Counselling Points
- Report muscle pain or weakness
- Monitor blood pressure and lipid levels
- Take with or without food
Serious warnings
- Risk of myopathy and rhabdomyolysis
- Elevated liver enzymes
- Increased risk of stroke
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