Canorof 25 mg Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Initial therapy for inflammatory and degenerative rheumatic diseases and mild to moderate pain.
Dosage (summary)
75 mg IM once daily, may increase to twice daily in severe cases; max 150 mg/day.
Onset of Action / Duration
Onset: 10-20 mins, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in late pregnancy; avoid during breastfeeding.
Key Drug Interactions
- Lithium
- Digoxin
- Anticoagulants
- Corticosteroids
- SSRIs
Contraindications
- Hypersensitivity to diclofenac
- Active gastrointestinal ulcers
- History of gastrointestinal bleeding
- Severe renal impairment
- Pregnancy after 20 weeks
- Lactation
Common side effects
- Gastrointestinal discomfort
- Headache
- Dizziness
- Skin rash
- Hypertension
Counselling Points
- Use the lowest effective dose
- Monitor for gastrointestinal symptoms
- Avoid in late pregnancy
- Report any skin reactions immediately
Serious warnings
- Risk of gastrointestinal bleeding
- Serious skin reactions
- DRESS syndrome
- Renal and hepatic effects
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