Capastat 1g Injection
PDF Leaflet Revision Date: 14 August 2009
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of pulmonary infections caused by resistant Mycobacterium tuberculosis.
Dosage (summary)
1 g daily IM for 60-120 days, then 1 g 2-3 times a week.
Onset of Action / Duration
Onset: 1-2 hours, Duration: Not specified.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Use only if benefits outweigh risks; safety not established.
Key Drug Interactions
- Streptomycin
- Amikacin
- Gentamicin
Contraindications
- Hypersensitivity to CAPASTAT
Common side effects
- Elevation of serum creatinine
- Auditory loss
- Eosinophilia
Counselling Points
- Monitor for renal function and electrolytes
- Audiometry before and during treatment
Serious warnings
- Ototoxicity risk
- Renal function monitoring required
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