Celecoxib Pfizer 100 mg. 200 mg Hard capsules

    Celecoxib Pfizer 100 mg. 200 mg Hard capsules

    S3
    PDF Leaflet Revision Date: 13 February 2022

    API: Celecoxib | Company: Upjohn South Africa

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Symptomatic treatment of inflammation and pain.

    Dosage (summary)

    Osteoarthritis: 200 mg daily; Rheumatoid arthritis: 100-200 mg twice daily; Post-operative pain: 100-200 mg; Dysmenorrhoea: 400 mg initially, then 200 mg; Ankylosing spondylitis: 200 mg daily.

    Special Populations

    • Elderly
    • Hepatic impairment
    • Renal impairment
    • CYP2C9 poor metabolisers

    Pregnancy & Breastfeeding

    Avoid in pregnancy; excreted in breast milk.

    Key Drug Interactions

    • Warfarin
    • Fluconazole
    • Diuretics
    • ACE inhibitors

    Contraindications

    • Hypersensitivity to celecoxib
    • Severe hepatic impairment
    • Severe renal impairment
    • Asthma related to NSAIDs
    • Pregnancy

    Common side effects

    • Hypertension
    • Dizziness
    • Gastrointestinal upset
    • Rash

    Counselling Points

    • Take with or without food
    • Monitor for cardiovascular symptoms
    • Report any skin reactions immediately

    Serious warnings

    • Cardiovascular events risk
    • Gastrointestinal complications
    • Serious skin reactions
    Important Disclaimer

    The Celecoxib Pfizer 100 mg. 200 mg Hard capsules professional information leaflet below is the property of Upjohn South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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