Clozapine Oethmaan 25 mg/50 mg/100 mg Tablet.
PDF Leaflet Revision Date: 02 August 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment-resistant schizophrenia and reducing suicidal behavior.
Dosage (summary)
Starting at 12.5 mg, titrate to 300-450 mg/day; max 900 mg/day.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid breastfeeding.
Key Drug Interactions
- CNS depressants
- Carbamazepine
- Benzodiazepines
Contraindications
- Hypersensitivity
- Severe bone marrow disorders
- History of agranulocytosis
Common side effects
- Sedation
- Weight gain
- Seizures
- Tachycardia
Counselling Points
- Monitor for infections
- Avoid activities requiring alertness
- Regular blood tests required
Serious warnings
- Risk of agranulocytosis
- Myocarditis
- Seizures
Important Disclaimer
The Clozapine Oethmaan 25 mg/50 mg/100 mg Tablet. professional information leaflet below is the property of Oethmaan Biosims and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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