Corolan 5mg. 7.5mg Tablet
PDF Leaflet Revision Date: 6 April 2017
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic treatment of chronic stable angina pectoris and chronic heart failure.
Dosage (summary)
Starting dose: 5 mg twice daily; may increase to 7.5 mg twice daily after 2-4 weeks if tolerated.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to teratogenic effects.
Key Drug Interactions
- Strong CYP3A4 inhibitors
- Moderate CYP3A4 inhibitors
- QT-prolonging medicines
Contraindications
- Hypersensitivity to ivabradine
- 3rd degree AV Block
- Pacemaker dependence
- Resting heart rate < 70 bpm
- Severe hypotension
- Cardiogenic shock
- Unstable heart failure
Common side effects
- Phosphenes
- Bradycardia
- Headache
- Dizziness
- Increased blood pressure
Counselling Points
- Take with food
- Monitor for signs of bradycardia
- Use effective contraception during treatment
Serious warnings
- Discontinue if no improvement in angina after 3 months
- Monitor heart rate regularly
- Risk of atrial fibrillation
Important Disclaimer
The Corolan 5mg. 7.5mg Tablet professional information leaflet below is the property of Servier Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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