Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets

    Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets

    S3
    PDF Leaflet Revision Date: 1 August 2022


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of hypertension and/or stable coronary artery disease and/or stable chronic heart failure.

    Dosage (summary)

    One tablet once daily; adjust for renal impairment.

    Special Populations

    • Renal impairment
    • Hepatic impairment
    • Elderly

    Pregnancy & Breastfeeding

    Contraindicated in pregnancy and breastfeeding.

    Key Drug Interactions

    • Potassium-sparing diuretics
    • Lithium
    • Aliskiren
    • Sacubitril/valsartan

    Contraindications

    • Hypersensitivity
    • Acute heart failure
    • Cardiogenic shock
    • Second or third degree AV block
    • Sick sinus syndrome
    • Symptomatic bradycardia
    • Severe bronchial asthma

    Common side effects

    • Headache
    • Dizziness
    • Hypotension
    • Nausea
    • Vomiting

    Counselling Points

    • Take in the morning before meals
    • Monitor blood pressure regularly
    • Report any signs of angioedema immediately

    Serious warnings

    • Hypotension
    • Angioedema
    • Neutropenia
    • Hepatic failure
    Important Disclaimer

    The Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets professional information leaflet below is the property of Servier Laboratories Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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