Cymgen 30 mg, 60 mg Capsules
PDF Leaflet Revision Date: 01 February 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression and diabetic peripheral neuropathic pain.
Dosage (summary)
60 mg once daily; 30 mg for renal/hepatic impairment.
Onset of Action / Duration
Onset: 2-4 weeks, Duration: Not specified.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- MAOIs
- CYP1A2 inhibitors
- CYP2D6 inhibitors
Contraindications
- Hypersensitivity to duloxetine
- Severe hepatic impairment
- Advanced renal impairment
- Concomitant MAOIs
- Under 18 years
Common side effects
- Nausea
- Headache
- Dry mouth
- Somnolence
- Dizziness
Counselling Points
- Monitor for suicidal ideation
- Avoid abrupt discontinuation
- Caution in driving or operating machinery
Serious warnings
- Increased risk of suicidal thoughts
- Serotonin syndrome
- Hypertension
- Withdrawal symptoms
Important Disclaimer
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