Damagus 200 Mg/2 Ml & 500 Mg/5 Ml 200 mg & 500 mg Solution for Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Routine and immediate reversal of neuromuscular blockade induced by rocuronium or vecuronium.
Dosage (summary)
4 mg/kg for routine reversal; 16 mg/kg for immediate reversal at 3 mins post rocuronium.
Special Populations
- Renal impairment
- Elderly patients
- Obese patients
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excretion in breast milk expected.
Key Drug Interactions
- Toremifene
- Fusidic acid
- Hormonal contraceptives
Contraindications
- Hypersensitivity to sugammadex
Common side effects
- Dysgeusia
- Cough
- Prolonged neuromuscular blockade
Counselling Points
- Monitor for recurrence of neuromuscular blockade.
- Ventilatory support may be required post-reversal.
- Caution with hormonal contraceptives.
Serious warnings
- Marked bradycardia
- Not for use with depolarising neuromuscular blockers
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