Muscudex 100 Mg/Ml 100 mg/ml Solution for injection

Muscudex 100 Mg/Ml 100 mg/ml Solution for injection

S4
PDF Leaflet Revision Date: 10 September 2024


Clinical Summary

Quick overview from the medicine insert

Indication

Reversal of neuromuscular blockade induced by rocuronium or vecuronium.

Dosage (summary)

4 mg/kg for profound blockade, 2 mg/kg for shallow blockade, 16 mg/kg for immediate reversal.

Special Populations

  • Renal impairment
  • Elderly patients
  • Hepatic impairment
  • Obese patients

Pregnancy & Breastfeeding

Safety not established in pregnancy; caution in breastfeeding.

Key Drug Interactions

  • Toremifene
  • Fusidic acid
  • Hormonal contraceptives

Contraindications

  • Hypersensitivity to sugammadex or excipients

Common side effects

  • Cough
  • Dysgeusia
  • Bradycardia
  • Hypotension

Counselling Points

  • Monitor for signs of recurrence of neuromuscular blockade.
  • Ventilatory support may be required post-administration.
  • Inform about potential hypersensitivity reactions.

Serious warnings

  • Risk of recurrence of neuromuscular blockade
  • Marked bradycardia may occur
  • Monitor for hypersensitivity reactions
Important Disclaimer

The Muscudex 100 Mg/Ml 100 mg/ml Solution for injection professional information leaflet below is the property of Adcock Ingram Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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