Muscudex 100 Mg/Ml 100 mg/ml Solution for injection
Clinical Summary
Quick overview from the medicine insert
Indication
Reversal of neuromuscular blockade induced by rocuronium or vecuronium.
Dosage (summary)
4 mg/kg for profound blockade, 2 mg/kg for shallow blockade, 16 mg/kg for immediate reversal.
Special Populations
- Renal impairment
- Elderly patients
- Hepatic impairment
- Obese patients
Pregnancy & Breastfeeding
Safety not established in pregnancy; caution in breastfeeding.
Key Drug Interactions
- Toremifene
- Fusidic acid
- Hormonal contraceptives
Contraindications
- Hypersensitivity to sugammadex or excipients
Common side effects
- Cough
- Dysgeusia
- Bradycardia
- Hypotension
Counselling Points
- Monitor for signs of recurrence of neuromuscular blockade.
- Ventilatory support may be required post-administration.
- Inform about potential hypersensitivity reactions.
Serious warnings
- Risk of recurrence of neuromuscular blockade
- Marked bradycardia may occur
- Monitor for hypersensitivity reactions
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