Dapinelat 30/60 30mg. 60mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of mild to moderate hypertension and prophylaxis of chronic stable angina pectoris.
Dosage (summary)
Initial dose: 30 mg once daily; max: 90 mg once daily.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Grapefruit juice
- Rifampicin
- Macrolide antibiotics
- Diltiazem
Contraindications
- Hypersensitivity to nifedipine
- Cardiogenic shock
- Aortic stenosis
- Myocardial infarction
- Gastrointestinal obstruction
Common side effects
- Headache
- Constipation
- Peripheral edema
- Dizziness
Counselling Points
- Swallow tablets whole
- Avoid grapefruit juice
- Monitor for hypotension
- Report any allergic reactions
Serious warnings
- Caution in hypotension
- Monitor blood pressure with IV magnesium sulfate
- Risk of obstructive symptoms
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