Daptomycin Equity 500 mg Powder for solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for complicated skin infections and Staphylococcus aureus bloodstream infections.
Dosage (summary)
cSSSI: 4 mg/kg IV daily for 7-14 days; Bacteraemia: 6 mg/kg IV daily for 2-6 weeks.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding due to safety concerns.
Key Drug Interactions
- Warfarin
- Tobramycin
- Probenecid
Contraindications
- Hypersensitivity to daptomycin
Common side effects
- Nausea
- Dizziness
- Rash
- Increased CPK
- Infusion site reactions
Counselling Points
- Monitor for muscle pain and CPK levels
- Avoid in pregnancy and breastfeeding
- Report any allergic reactions immediately
Serious warnings
- Risk of myopathy
- Not effective for pneumonia
- Anaphylaxis risk
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