Ddavp Is 0.1 mg / 1ml Intranasal Solution
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of vasopressin sensitive central diabetes insipidus.
Dosage (summary)
Adults: 10-20 u03bcg intranasally 1-2 times daily.
Onset of Action / Duration
Onset: 2 hours, Duration: 4-8 hours
Special Populations
- Elderly
- Children
- Renal impairment
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established; minimal transfer to breast milk.
Key Drug Interactions
- Tricyclic antidepressants
- SSRIs
- NSAIDs
- Carbamazepine
Contraindications
- Renal diabetes insipidus
- Hypersensitivity
- Peripheral vascular disease
- Cardiac insufficiency
- Cirrhosis
- Hypertension
- SIADH
Common side effects
- Nasal congestion
- Epistaxis
- Abdominal pain
- Nausea
- Headache
Counselling Points
- Limit fluid intake before and after administration
- Monitor for signs of hyponatraemia
- Use under adult supervision in children
Serious warnings
- Risk of overhydration
- Monitor fluid intake
- Caution in elderly and children
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