Desugomyl 100 Mg/Ml 100 mg Solution for Injection

    Desugomyl 100 Mg/Ml 100 mg Solution for Injection

    S4
    PDF Leaflet Revision Date: 22 November 2022

    API: Sugammadex Sodium | Company: Mylan

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Routine and immediate reversal of neuromuscular blockade induced by rocuronium or vecuronium.

    Dosage (summary)

    4 mg/kg for profound blockade, 2 mg/kg for shallow blockade, 16 mg/kg for immediate reversal.

    Onset of Action / Duration

    Onset: 3 mins, Duration: varies based on dose.

    Special Populations

    • Renal impairment
    • Elderly patients
    • Hepatic impairment
    • Obese patients
    • Paediatric patients

    Pregnancy & Breastfeeding

    Caution in pregnancy; unknown if excreted in breast milk.

    Key Drug Interactions

    • Toremifene
    • Fusidic acid
    • Hormonal contraceptives

    Contraindications

    • Hypersensitivity to sugammadex or excipients
    • Severe renal impairment

    Common side effects

    • Hypersensitivity reactions
    • Cough
    • Airway complications
    • Procedural hypotension

    Counselling Points

    • Monitor for signs of recurrence of neuromuscular blockade.
    • Ventilatory support may be required post-reversal.
    • Inform about potential hypersensitivity reactions.

    Serious warnings

    • Risk of recurrence of neuromuscular blockade
    • Marked bradycardia
    • Monitor respiratory function post-reversal
    Important Disclaimer

    The Desugomyl 100 Mg/Ml 100 mg Solution for Injection professional information leaflet below is the property of Mylan and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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