Diflucan Capsules, Diflucan Capsules, Powder For Oral Suspension 50 mg, 150 mg and 200 mg & 50 mg/5 mL and 200 mg/5 mL CAPSULES, INFUSION,
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of fungal infections including cryptococcal meningitis and candidiasis.
Dosage (summary)
400 mg on day 1, then 200 mg daily for cryptococcal meningitis; 150 mg as a single dose for vaginal candidiasis.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy; found in breast milk.
Key Drug Interactions
- Terfenadine
- Cisapride
- Erythromycin
Contraindications
- Hypersensitivity to fluconazole
- Co-administration with terfenadine at high doses
Common side effects
- Headache
- Nausea
- Rash
Counselling Points
- Monitor for liver function
- Avoid in pregnancy
- Use effective contraception during treatment
Serious warnings
- Hepatotoxicity
- QT prolongation
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