Dizalet 40mg Capsules
PDF Leaflet Revision Date: 24 April 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of metastatic castration-resistant prostate cancer in adult men.
Dosage (summary)
160 mg (four 40 mg capsules) once daily.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in women; unknown if excreted in breast milk.
Key Drug Interactions
- CYP2C8 inhibitors/inducers
- CYP3A4 inhibitors/inducers
- Medicines prolonging QT interval
Contraindications
- Hypersensitivity to enzalutamide
- Not for use in women
Common side effects
- Asthenia/fatigue
- Hot flushes
- Headache
- Hypertension
Counselling Points
- Take whole with water
- Use contraception during and for 4 months after treatment
- May affect ability to drive or operate machinery
Serious warnings
- Risk of seizure
- Posterior reversible encephalopathy syndrome
Important Disclaimer
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