Duoforce Film coated tablets.
PDF Leaflet Revision Date: 04 May 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of mild to moderate essential hypertension.
Dosage (summary)
One tablet daily; no adjustment for elderly or mild to moderate renal impairment.
Onset of Action / Duration
Onset: 2 hours, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; can cause fetal harm.
Key Drug Interactions
- Lithium
- Potassium-sparing diuretics
- NSAIDs
- CYP3A4 inhibitors
Contraindications
- Hypersensitivity
- Angioedema history
- Severe renal impairment
- Severe hepatic impairment
- Pregnancy and lactation
Common side effects
- Dizziness
- Headache
- Fatigue
- Hypotension
- Edema
Counselling Points
- Take with water
- Monitor blood pressure regularly
- Avoid grapefruit juice
- Report any signs of angioedema
Serious warnings
- Risk of hypotension in volume-depleted patients
- Angioedema risk
- Caution in heart failure
Important Disclaimer
The Duoforce Film coated tablets. professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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