Dronamyl 4 mg/5 ml Concentrate for dilution for infusion
PDF Leaflet Revision Date: 09 February 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of tumour-induced hypercalcaemia and skeletal conditions in advanced malignancies.
Dosage (summary)
4 mg IV infusion every 3-4 weeks; hydration required.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Aminoglycosides
- Calcitonin
- Loop diuretics
- Nephrotoxic medicines
Contraindications
- Hypersensitivity to zoledronic acid
- Severe renal impairment
- Pregnancy
- Lactation
- Children
Common side effects
- Renal impairment
- Bone pain
- Nausea
- Fever
- Acute phase reaction
Counselling Points
- Maintain hydration
- Monitor renal function
- Report any thigh or groin pain
- Avoid invasive dental procedures
Serious warnings
- Risk of renal dysfunction
- Osteonecrosis of the jaw
- Hypocalcaemia
- Atypical femur fractures
Important Disclaimer
The Dronamyl 4 mg/5 ml Concentrate for dilution for infusion professional information leaflet below is the property of Viatris Healthcare and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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