Duopic 150/75 150mg, 75mg Tablet
PDF Leaflet Revision Date: 31 May 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of pulmonary tuberculosis in the continuation phase.
Dosage (summary)
Daily dose based on body weight: 2-5 tablets (150 mg rifampicin, 75 mg isoniazid).
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; contraindicated in breastfeeding due to excretion in milk.
Key Drug Interactions
- Saquinavir/ritonavir
- Alcohol
- Antiepileptics
Contraindications
- Hypersensitivity to rifamycins or isoniazid
- Jaundice
- Liver damage
Common side effects
- Nausea
- Vomiting
- Headache
- Dizziness
Counselling Points
- Take with water
- Avoid alcohol
- Monitor for liver symptoms
Serious warnings
- Risk of severe hepatitis
- Monitor liver function
- Severe skin reactions
Important Disclaimer
The Duopic 150/75 150mg, 75mg Tablet professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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