Easan 150 mg Powder for solution for infusion

    Easan 150 mg Powder for solution for infusion

    S4
    PDF Leaflet Revision Date: 7 March 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Prevention of nausea and vomiting associated with cancer chemotherapy.

    Dosage (summary)

    150 mg IV on Day 1, no adjustment for elderly or renal impairment.

    Onset of Action / Duration

    Onset: 30 mins, Duration: Not specified.

    Special Populations

    • Moderate hepatic impairment
    • Severe hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Not recommended in pregnancy; breastfeeding not advised.

    Key Drug Interactions

    • CYP3A4 inhibitors
    • CYP3A4 inducers
    • Warfarin

    Contraindications

    • Hypersensitivity to aprepitant
    • Co-administration with pimozide
    • Pregnancy
    • Breastfeeding
    • Paediatric patients

    Common side effects

    • Fatigue
    • Headache
    • Constipation
    • Dyspepsia
    • Hiccups

    Counselling Points

    • Monitor for hypersensitivity
    • Use non-hormonal contraception
    • Avoid in pregnancy and breastfeeding

    Serious warnings

    • Hypersensitivity reactions
    • Infusion site reactions
    • Caution in hepatic impairment
    Important Disclaimer

    The Easan 150 mg Powder for solution for infusion professional information leaflet below is the property of Kahma Biotech and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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