Dapicub 500 mg Powder for solution for infusion

    Dapicub 500 mg Powder for solution for infusion

    S4
    PDF Leaflet Revision Date: 14 March 2023

    API: Daptomycin | Company: Kahma Biotech

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Complicated skin and skin structure infections and Staphylococcus aureus bloodstream infections.

    Dosage (summary)

    cSSTI: 4 mg/kg once daily for 7-14 days; SAB: 6 mg/kg once daily for 2-6 weeks.

    Special Populations

    • Renal impairment
    • Hepatic impairment
    • Elderly

    Pregnancy & Breastfeeding

    Safety in pregnancy and breastfeeding not established.

    Key Drug Interactions

    • Myopathy with HMG-CoA reductase inhibitors
    • False PT/INR prolongation
    • Caution with tobramycin

    Contraindications

    • Hypersensitivity to daptomycin

    Common side effects

    • Fungal infections
    • Anemia
    • Dizziness
    • Nausea
    • Rash

    Counselling Points

    • Monitor for muscle pain and CPK levels
    • Avoid driving if dizziness occurs
    • Report any signs of allergic reactions

    Serious warnings

    • Risk of Clostridium difficile-associated diarrhea
    • Eosinophilic pneumonia
    • Renal impairment
    Important Disclaimer

    The Dapicub 500 mg Powder for solution for infusion professional information leaflet below is the property of Kahma Biotech and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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