Efamat 50 mg, 100 mg, 200 mg FC tablet
PDF Leaflet Revision Date: 14 August 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 in adults, adolescents, and children over 3 years and 13 kg.
Dosage (summary)
Adults: 600 mg orally once daily, preferably at bedtime.
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- CYP3A4 inducers/inhibitors
- St. John's wort
- Cisapride
- Midazolam
Contraindications
- Hypersensitivity to efavirenz
- Severe hepatic impairment
- Concurrent use with certain medications
Common side effects
- Rash
- Dizziness
- Nausea
- Headache
- Fatigue
Counselling Points
- Take on an empty stomach
- Use barrier contraception
- Monitor for psychiatric symptoms
Serious warnings
- Serious psychiatric reactions
- Risk of seizures
- QTc prolongation
Important Disclaimer
The Efamat 50 mg, 100 mg, 200 mg FC tablet professional information leaflet below is the property of Viatris Healthcare (Pty)Ltd and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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