Emistop 4mg & 8 mg Injection (aqueous solution).
Clinical Summary
Quick overview from the medicine insert
Indication
Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative.
Dosage (summary)
Adults: 8 mg IV/IM before treatment, then 8 mg orally every 12 hours.
Onset of Action / Duration
Onset: 30 mins, Duration: Up to 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in first 12 weeks of pregnancy; avoid breastfeeding.
Key Drug Interactions
- Apomorphine
- CYP3A4 inducers
- QT prolonging agents
Contraindications
- Hypersensitivity to ondansetron
- Pregnancy
- Congenital long QT syndrome
Common side effects
- Headache
- Dizziness
- Constipation
- Hypotension
Counselling Points
- Monitor for signs of QT prolongation.
- Avoid use in early pregnancy.
- Report any severe allergic reactions.
Serious warnings
- QT prolongation
- Myocardial ischemia
- Serotonin syndrome
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