Epanutin Ready Mixed Parenteral Injection 5 mL Solution for injection
PDF Leaflet Revision Date: 14 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention and treatment of seizures during or after neurosurgery and control of status epilepticus.
Dosage (summary)
Adults: Loading dose 10-15 mg/kg IV, maintenance 300-400 mg daily. Neonates: 10-20 mg/kg IV.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
May cause fetal harm; avoid in pregnancy and breastfeeding.
Key Drug Interactions
- Alcohol
- Anticonvulsants
- Antibiotics
- Antiretrovirals
Contraindications
- Hypersensitivity to phenytoin
- Porphyria
- AV block
- Severe cardiac dysrhythmias
Common side effects
- Dizziness
- Nausea
- Hypotension
- Gingival hyperplasia
Counselling Points
- Monitor for rash
- Avoid rapid IV administration
- Use effective contraception in women of childbearing potential
Serious warnings
- Cardiovascular collapse
- CNS depression
- Local toxicity
- HSS/DRESS
Important Disclaimer
The Epanutin Ready Mixed Parenteral Injection 5 mL Solution for injection professional information leaflet below is the property of Viatris Healthcare and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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