Epirol 200mg Tablet
PDF Leaflet Revision Date: 15 October 1984
Clinical Summary
Quick overview from the medicine insert
Indication
Used for petit mal, grand mal, and temporal lobe epilepsy.
Dosage (summary)
Adults: Start at 600 mg/day, increase by 200 mg every 3 days; max 2600 mg/day. Children: 20-50 mg/kg/day based on weight.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Avoid in pregnancy unless essential; teratogenic risk in first trimester.
Key Drug Interactions
- May enhance sedative effects of barbiturates
- Potentiates MAO inhibitors
Contraindications
- Pregnancy
- Hepatic dysfunction
Common side effects
- Nausea
- Tremor
- Hair loss
- Gastric irritation
Counselling Points
- Take with food
- Monitor for bleeding
- Report abdominal pain
- Avoid in pregnancy
Serious warnings
- Risk of hepatic failure
- Monitor liver function
- Potential for hyperammonaemia
Important Disclaimer
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