Equity Methadone 2 mg / 1 ml Oral Solution
Clinical Summary
Quick overview from the medicine insert
Indication
Substitution treatment in opiate dependence.
Dosage (summary)
Initial: 20 mg once daily, adjust to 60-120 mg based on clinical assessment.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- CNS depressants
Contraindications
- Hypersensitivity
- Respiratory depression
- Acute obstructive airway disease
- Children
Common side effects
- Respiratory depression
- Nausea
- Constipation
- Sedation
Counselling Points
- Avoid alcohol and CNS depressants
- Store safely away from children
- Monitor for signs of overdose
Serious warnings
- QT prolongation
- Risk of overdose
- Addiction potential
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