Etoposide-Hexal 50mg / 2.5ml. 100mg / 5ml. 200mg / 10ml. 400mg / 20ml. 1000mg / 50ml Infusion

Etoposide-Hexal 50mg / 2.5ml. 100mg / 5ml. 200mg / 10ml. 400mg / 20ml. 1000mg / 50ml Infusion

S4
PDF Leaflet Revision Date: 29 June 2019

API: Etoposide | Company: Sandoz

Clinical Summary

Quick overview from the medicine insert

Indication

Management of testicular and small cell lung tumors.

Dosage (summary)

IV: 50-100 mg/mu00b2/day for 5 days or 100 mg/mu00b2 on days 1, 3, 5 every 3-4 weeks.

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Can cause fetal harm; effective contraception required during treatment.

Key Drug Interactions

  • Ciclosporin
  • Cisplatin
  • Phenytoin
  • Warfarin

Contraindications

  • Hypersensitivity to etoposide
  • Severe hepatic dysfunction
  • Bone marrow depression
  • Renal impairment

Common side effects

  • Myelosuppression
  • Leukopenia
  • Thrombocytopenia
  • Anaphylactic reactions
  • Nausea

Counselling Points

  • Monitor for signs of infection
  • Avoid live vaccines
  • Report any bleeding or bruising

Serious warnings

  • Severe myelosuppression
  • Risk of anaphylaxis
  • Tumor lysis syndrome
Important Disclaimer

The Etoposide-Hexal 50mg / 2.5ml. 100mg / 5ml. 200mg / 10ml. 400mg / 20ml. 1000mg / 50ml Infusion professional information leaflet below is the property of Sandoz and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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