Exlov XR 50 Mg/ 100 Mg 50 mg/ 100 mg XR tablet
PDF Leaflet Revision Date: 05 October 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of major depressive disorder (MDD).
Dosage (summary)
50 mg once daily, max 100 mg; adjust for renal impairment.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; may cause complications in neonates.
Key Drug Interactions
- MAOIs
- CNS-active medicines
- Serotonergic drugs
Contraindications
- Hypersensitivity to desvenlafaxine
- Use in children <18 years
- Pregnancy and lactation
Common side effects
- Nausea
- Dizziness
- Increased blood pressure
- Fatigue
Counselling Points
- Monitor for worsening depression
- Avoid alcohol
- Caution with driving or machinery
Serious warnings
- Risk of suicidality
- Serotonin syndrome
- Discontinuation symptoms
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